Inorganic voltage nanosensors

Speaker
Shimon Weiss
Date
06/01/2015 - 16:00Add to Calendar 2015-01-06 16:00:00 2015-01-06 16:00:00 Inorganic voltage nanosensors We have been developing targetable voltage sensing inorganic nanoparticles (vsNPs) that are designed to self-insert into the cell membrane and optically record, non-invasively, action potential on the single-particle level, at multi-sites and in a large field-of-view. Using the first generation of vsNPs, we have measured large quantum confined Stark effect (QCSE) shifts as function of voltage (in-vitro, using electrodes). We have recently developed functionalization and membrane insertion schemes for these probes, and have demonstrated, for the first time, membrane voltage sensing with them. Physics Building (202) Room 301 המחלקה לפיזיקה physics.dept@mail.biu.ac.il Asia/Jerusalem public
Place
Physics Building (202) Room 301
Abstract
We have been developing targetable voltage sensing inorganic nanoparticles (vsNPs) that are designed to self-insert into the cell membrane and optically record, non-invasively, action potential on the single-particle level, at multi-sites and in a large field-of-view. Using the first generation of vsNPs, we have measured large quantum confined Stark effect (QCSE) shifts as function of voltage (in-vitro, using electrodes). We have recently developed functionalization and membrane insertion schemes for these probes, and have demonstrated, for the first time, membrane voltage sensing with them.

תאריך עדכון אחרון : 04/01/2015