The surprising challenge of growing slowly
Seminar
מועמד למחלקה
Off
Speaker
Rami Pugatch
Date
-
Add to Calendar
2026-06-17 10:30:00
2026-06-17 11:30:00
The surprising challenge of growing slowly
All single-cell organisms share a universal autocatalytic architecture first discovered theoretically by John von-Neumann, that facilitates cellular self-reproduction. We explain von-Neuman's model, and how our modern understanding of molecular cell biology and the central dogma is contained in it. We explain how we previously derived the phenomenological ribosome growth law, as well as other growth laws from this model, and consider our new contribution, a universal shot noise limit on slow growth with broad implications on how cells adapt to growth in harsh environments, and different lifestyles that require different control laws to govern their modus operandi in different environments.
Seminar room 303
המחלקה לפיזיקה
physics.dept@mail.biu.ac.il
Asia/Jerusalem
public
Place
Seminar room 303
Abstract
All single-cell organisms share a universal autocatalytic architecture first discovered theoretically by John von-Neumann, that facilitates cellular self-reproduction. We explain von-Neuman's model, and how our modern understanding of molecular cell biology and the central dogma is contained in it. We explain how we previously derived the phenomenological ribosome growth law, as well as other growth laws from this model, and consider our new contribution, a universal shot noise limit on slow growth with broad implications on how cells adapt to growth in harsh environments, and different lifestyles that require different control laws to govern their modus operandi in different environments.
תאריך עדכון אחרון : 14/06/2026