Evolution of SARS-CoV-2 between and within hosts
Seminar
QUEST Center event
No
Speaker
Daniel Weissman
Date
03/07/2023 - 11:30 - 10:30Add to Calendar
2023-07-03 10:30:10
2023-07-03 11:30:11
Evolution of SARS-CoV-2 between and within hosts
The global population of SARS-CoV-2 is structured into discrete infections within hosts. How does this affect the evolution of the pandemic? First, I will show how one can use the evolution between pairs of hosts to infer how many virus particles contribute to a new infection. Second, I will discuss how the observed timing and dynamics of the Variants of Concern suggest that rare chronic infections are the key drivers of global infection. Finally, I will briefly touch on a case study of rapid evolution and diversification within a chronic infection.
Rm 303
המחלקה לפיזיקה
physics.dept@mail.biu.ac.il
Asia/Jerusalem
public
Place
Rm 303
Abstract
The global population of SARS-CoV-2 is structured into discrete infections within hosts. How does this affect the evolution of the pandemic? First, I will show how one can use the evolution between pairs of hosts to infer how many virus particles contribute to a new infection. Second, I will discuss how the observed timing and dynamics of the Variants of Concern suggest that rare chronic infections are the key drivers of global infection. Finally, I will briefly touch on a case study of rapid evolution and diversification within a chronic infection.
תאריך עדכון אחרון : 29/06/2023
