Stochasticity of Intracellular Transport

Seminar
Speaker
דר' סטס בורוב
Date
24/12/2013 - 16:30Add to Calendar 2013-12-24 16:30:00 2013-12-24 16:30:00 Stochasticity of Intracellular Transport This talk will describe quantitative analyses of particle tracking data for  systems with cytoskeletally associated motors to better understand the  motions contributing to intracellular transport and, more generally, means  for characterizing systems far from equilibrium. We exploit stochastic properties  of single particle trajectories to establish "sanity" tests for experimentally  collected data. Development of simple order parameters for 2d motion  and studying its behavior for different models of transport in disordered media  permits us to distinguish between random motion inside dense physical systems  and molecular motors mediated transport. Furthermore, the stochastic properties  of insulin-containg vesicles transport in beta cells provide a simple mechanism for how  important beta cell functioning (biphasic insulin secretion) can arise. Resnick Building (209), seminar room 210 המחלקה לפיזיקה physics.dept@mail.biu.ac.il Asia/Jerusalem public
Place
Resnick Building (209), seminar room 210
Abstract

This talk will describe quantitative analyses of particle tracking data for 
systems with cytoskeletally associated motors to better understand the 
motions contributing to intracellular transport and, more generally, means 
for characterizing systems far from equilibrium. We exploit stochastic properties 
of single particle trajectories to establish "sanity" tests for experimentally 
collected data. Development of simple order parameters for 2d motion 
and studying its behavior for different models of transport in disordered media 
permits us to distinguish between random motion inside dense physical systems 
and molecular motors mediated transport. Furthermore, the stochastic properties 
of insulin-containg vesicles transport in beta cells provide a simple mechanism for how 
important beta cell functioning (biphasic insulin secretion) can arise.

תאריך עדכון אחרון : 17/12/2013