Relaxometry of Superparamagnetic Magnetite Nanoparticles

Speaker
Amit Finkler (Stuttgart)
Date
27/12/2015 - 16:00 - 15:00Add to Calendar 2015-12-27 15:00:00 2015-12-27 16:00:00 Relaxometry of Superparamagnetic Magnetite Nanoparticles We present a novel technique to image superparamagnetic iron oxide nanoparticles via their fluctuating magnetic fields. The detection is based on the nitrogen-vacancy (NV) color center in diamond, which allows optically detected magnetic resonance (ODMR) measurements on its electron spin structure. In combination with an atomic-force-microscope, this atomic-sized color center maps ambient magnetic fields in a wide frequency range from DC up to several GHz [1], while retaining a high spatial resolution in the sub-nanometer range [2]. We demonstrate imaging of single 10 nm sized magnetite nanoparticles using this spin noise detection technique. By fitting simulations (Ornstein-Uhlenbeck process) to the data, we are able to infer additional information on such a particle and its dynamics, like the attempt frequency and the anisotropy constant [3]. This is of high interest to the proposed application of magnetite nanoparticles as an alternative MRI contrast agent or to the field of particle-aided tumor hyperthermia. [1] E. Schäfer-Nolte et al., Phys. Rev. Lett. 113, 217204 (2014) [2] P. Maletinsky et al., Nat. Nanotech. 7, 320 (2012) [3] D. Schmid-Lorch et al., Nano Lett. 15, 4942 (2015) Resnick Building (209), room 210 Department of Physics physics.dept@mail.biu.ac.il Asia/Jerusalem public
Place
Resnick Building (209), room 210
Abstract


We present a novel technique to image superparamagnetic iron oxide nanoparticles via their fluctuating magnetic fields. The detection is based on the nitrogen-vacancy (NV) color center in diamond, which allows optically detected magnetic resonance (ODMR) measurements on its electron spin structure. In combination with an atomic-force-microscope, this atomic-sized color center maps ambient magnetic fields in a wide frequency range from DC up to several GHz [1], while retaining a high spatial resolution in the sub-nanometer range
[2]. We demonstrate imaging of single 10 nm sized magnetite nanoparticles using this spin noise detection technique. By fitting simulations (Ornstein-Uhlenbeck process) to the data, we are able to infer additional information on such a particle and its dynamics, like the attempt frequency and the anisotropy constant [3]. This is of high interest to the proposed application of magnetite nanoparticles as an alternative MRI contrast agent or to the field of particle-aided tumor hyperthermia.

[1] E. Schäfer-Nolte et al., Phys. Rev. Lett. 113, 217204 (2014)
[2] P. Maletinsky et al., Nat. Nanotech. 7, 320 (2012)
[3] D. Schmid-Lorch et al., Nano Lett. 15, 4942 (2015)

Last Updated Date : 05/10/2015